Technical University of Munich Plastic Surgery & Regenerative Medicine
Shanghai Ninth People's Hospital, SJTU · Dept. of Plastic & Reconstructive Surgery
戴心怡
DAI XINYI · M.D. / Ph.D
Associate Chief Physician | Plastic Surgery & Regenerative Medicine
Harvard · NYU · Johns Hopkins Am. Association of Plastic Surgeons
Shanghai Science & Technology Commission Class A · 2019
Principal Investigator General Program · 2021
About
About Me
Xinyi Dai M.D. / Ph.D
Associate Chief Physician
Medical Humanities & Surgical Artistry
Surgical Artistry: Like micro-reconstruction, Chinese calligraphy demands perfect hand stability, patience, and structural harmony.
Xinyi Dai M.D. / Ph.D
Associate Chief Physician · Dept. of Plastic & Reconstructive Surgery · Shanghai Ninth People's Hospital
Xinyi Dai is an Associate Chief Physician in the Department of Plastic and Reconstructive Surgery at Shanghai Ninth People's Hospital, affiliated with Shanghai Jiao Tong University School of Medicine. He is an AAPS Constable Fellow, a member of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), and a recipient of Shanghai's Pujiang Talent Program.
From 2012 to 2016, supported by the China Scholarship Council (CSC), he pursued his doctoral studies at the Technical University of Munich (TUM), Germany, graduating with the highest distinction "Summa Cum Laude" in Plastic Surgery and Regenerative Medicine.
In 2014, selected through international competitive review from over 29 countries, he received the AAPS John D. Constable International Travelling Fellowship and was invited to train at Harvard Medical School's Massachusetts General Hospital, NYU Langone Medical Center, and Johns Hopkins Hospital.
From 2016 to 2017, he conducted postdoctoral research at the University Medical Center Göttingen, Germany, focusing on the mechanisms of scarless wound healing and their translational applications. His representative paper was published in NPG Asia Materials (Nature portfolio) and highlighted in Science Translational Medicine.
He contributed to the Science special issue "125 Questions: Exploration and Discovery." He is the chief editor of a 100,000-word popular science book on tissue defect repair and regeneration, published by Shanghai Jiao Tong University Press.
Ph.D — Summa Cum Laude
Technical University of Munich, specialization in Plastic Surgery and Regenerative Medicine
AAPS Constable Fellow
Selected through international competition to train at Harvard MGH, NYU Langone, and Johns Hopkins
Nature Portfolio Publication
Research published in NPG Asia Materials and highlighted in Science Translational Medicine
Shanghai Pujiang Talent (Class A)
Principal Investigator on NSFC General Program and Shanghai Pujiang Talent Plan
Granted Invention Patent
Medical Thermosensitive Hydrogel Dressing and Preparation Method
ZL 2022 1 0532841.1 · Granted: 2023.11.21Clinical Expertise
Expertise
Specializing in reconstruction of tissue defects caused by trauma, tumors, and disease, with deep expertise in both clinical practice and translational research
Trauma & Tissue Defect Repair
Trauma & Tissue Defect Repair
Microsurgical reconstruction of traumatic, tumor-related, and disease-induced tissue defects, including replantation and complex wound management with functional and aesthetic restoration.
Microsurgical Reconstruction
Microsurgical Reconstruction
Application of microsurgical techniques for tissue transplantation and vascular anastomosis, achieving precise, high-quality reconstruction of composite tissue defects.
Oncoplastic Surgery
Oncoplastic Surgery
Resection and reconstruction of benign and malignant skin/soft tissue tumors, balancing radical treatment with aesthetic outcomes to minimize post-operative functional impact.
Scar & Functional Repair
Scar & Functional Repair
Functional and aesthetic correction of scar deformities and extremity malformations, restoring normal appearance and function for patients.
Tissue Engineering & Regenerative Medicine
Tissue Engineering & Regenerative Medicine
Research into mechanisms of scarless wound healing, development of nano-biomaterial drug-delivery systems, and translational application of electrospun scaffolds.
Medical Aesthetics
Medical Aesthetics
Blepharoplasty, brow lifting, and injection aesthetics (botulinum toxin, hyaluronic acid), combining medical precision with natural aesthetic enhancement.
Education & Training
Education & Training
Clinical
Shanghai Ninth People's Hospital, SJTU
Dept. of Plastic & Reconstructive Surgery · Associate Chief Physician
Leading an NSFC-funded general program project focused on molecular mechanisms of scarless wound healing and translational nano-biomaterial applications.
Postdoc
University Medical Center Göttingen
Universitätsmedizin Göttingen, Germany
Postdoctoral research on the mechanisms of scarless wound healing and translational applications. Representative publication in NPG Asia Materials (Nature portfolio), highlighted in Science Translational Medicine.
Fellowship
AAPS John D. Constable Fellowship
American Association of Plastic Surgeons · International Competitive Selection
Selected from applicants across 29 countries for the AAPS annual international travelling fellowship. Visited Harvard MGH, NYU Langone Medical Center, and Johns Hopkins Hospital.
Ph.D
Technical University of Munich
Technische Universität München (TUM), Germany
Supported by China Scholarship Council (CSC 201208310668). Specialization: Plastic Surgery and Regenerative Medicine. Graduated with the highest distinction "Summa Cum Laude."
M.D.
Shanghai Jiao Tong University School of Medicine
Shanghai Jiao Tong University School of Medicine
Awarded M.D. degree in Clinical Medicine. Subsequently joined the Department of Plastic Surgery at Shanghai First People's Hospital.
Research & Grants
Research & Grants
Funded Projects
National Natural Science Foundation of China General Program Completed
Mechanism of LncRNA TCF4-AS1 trans-acting on MCP-1 transcriptional regulation in nano-curcumin dimer-induced scarless wound healing
Grant No.: 82072174 · Role: PIShanghai Science and Technology Commission Pujiang Talent Plan (Class A) Completed
Mechanism of EMMPRIN in inhibiting post-wound scar formation via the Wnt signaling pathway
Grant No.: 19PJ1408600 · Role: PIPatents
Medical Thermosensitive Hydrogel Dressing and Preparation Method
Patent No.: ZL 2022 1 0532841.1
Granted: 2023.11.21
Inventors: Yi Shen, Xinyi Dai
A Method for Wound Repair by Activating Fibroblasts
Patent No.: CN119215023A
Filed: 2024.09.27
Applicants: Xinyi Dai, Yi Shen
Publications
Publications
Journal Articles
Wei Nie, Eric J. Marrotte, Rongyuan Xie, Hans-Gunther Machens, Arndt F. Schilling, Yi Shen, Michael Seeds, Anthony Atala, Xinyi Dai
Towards scarless repair: MMP-2 responsive drug releasing nanofibrous mat restores homeostasis via fibroblasts' activation.
Composites Part B: Engineering. 2025; Vol. 291, 111972.
Dai X, Nie W, Shen H, Machens HG, Boker K, Taheri S, Lehmann W, Shen Y, Schilling AF.
Electrospinning based biomaterials for biomimetic fabrication, bioactive protein delivery and wound regenerative repair.
Regenerative Biomaterials. 2024; Dec 3; 12:rbae139.
Xinyi Dai, Juan Liu, Huaiyuan Zheng, Johannes Wichmann, Ursula Hopfner, Stefanie Sudhop, Carina Prein, Yi Shen, Hans Machens, Arndt Schilling.
Nano-formulated curcumin accelerates acute wound healing through Dkk-1 mediated fibroblast mobilization and MCP-1 mediated anti-inflammation.
NPG Asia Materials. 2017; (9), e368. Science Translational Medicine Highlight
Eberlin KR, Del Frari B, Dai X, Austen WG Jr.
The John D. Constable International Traveling Fellowship: A Reciprocal Education in Plastic Surgery.
Journal of Craniofacial Surgery. 2015; Jun; 26(4):1050-2.
Popular Science Book · Chief Editor
《缺失的拼图：组织缺损修复与再生的奇妙世界》
上海交通大学出版社 · 10万字 · ISBN: 978-7-313-30847-4Awards & International Exchange
Awards & International Exchange
Honors & Awards
Shanghai Pujiang Talent Program (Class A)
Shanghai Science and Technology Commission
AAPS John D. Constable Travelling Fellowship
American Association of Plastic Surgeons (AAPS)
National Government-funded Doctoral Scholarship
China Scholarship Council (CSC 201208310668)
International Conferences
TERMIS-AM Annual Meeting
San Diego, USA
4th TERMIS World Congress
Boston, USA
19. Chirurgische Forschungstage
Wurzburg, Germany
26th Sino-German Medical Meeting
Essen, Germany
Visited Institutions
Massachusetts General Hospital
Harvard Medical School
Boston, USANYU Langone Medical Center
New York University
New York, USAJohns Hopkins Hospital
Johns Hopkins University
Baltimore, USATechnische Universitat Munchen
TUM School of Medicine
Munich, GermanyUniversitatsmedizin Gottingen
University of Gottingen
Gottingen, GermanyLanguage Skills
Chinese Native
English TOEFL 90
German Goethe B2
Contact
Contact
For appointments or academic collaboration, please reach out through the options below
Address
Shanghai Ninth People's Hospital affiliated to SJTU
Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine Department of Plastic & Reconstructive SurgeryClinic Information
- Department
- Plastic & Reconstructive Surgery
- Title
- Associate Chief Physician
- Expertise
- Tissue Defect Repair · Microsurgery · Scar Treatment
Academic Collaboration
Interested in research collaboration in tissue engineering, regenerative medicine, and plastic surgery.
AAPS Fellow · TERMIS Member · Pujiang TalentMedical note: This page introduces professional credentials, research interests, and clinic information only. It is not a substitute for in-person consultation, diagnosis, or treatment.